The world’s most severe virus infection
31-Aug-08
Dede, now 37, is an Indonesian who accidentally cut his knee while working as a builder at a building site at 15 years of age. It was only a small wound, but a few weeks later a small wart then developed on his lower leg, then spread uncontrollably throughout his body.
The condition manifested itself as horn-like extensions, or gnarled growths, so big and thick that they looked like “twisted tree roots growing out of his skin.”
It had caused him, over time, to be sacked from his job by his early 20s, left by his wife of 10 years and shunned by neighbours. His 2 children had to be taken care of by relatives.
He was nicknamed the “Tree Man”.
It’s not that he didn’t try to find a cure before: Indonesian doctors tried their best, even burning off some of his growths, but the growths simply came back a few weeks later, and the growth rate was even faster!
Then, it was only natural that Dede’s worst fear was that the warts would completely cover his face, making him blind and starving him to death.
It was diagnosed as an extremely rare severe Human Papilloma Virus (HPV) infection by Dr Anthony Gaspari, American dermatologist. In fact HPV is a “fairly common infection” where in normal cases, it only causes small warts to develop. However, in Dede’s case, he has a rare genetic fault that gets in the way of his immune system: his body cannot deal with the warts. Hence, the virus was able to:
hijack the cellular machinery of his skin cells, ordering them to produce massive amounts of the substance that caused the tree-like growths known as “cutaneous horns” on his hands and feet.
The condition became so bad that it became life-threatening, as the warts caused a lung infection which necessitated his hospitalisation in early 2008.
By the end of his 9-month stay in hospital, 6 kg of warts were surgically removed from his body. In all, 95% of the warts had been removed.
Finally on 26th August 2008 he was cleared to go home so that he could observe the Islamic fasting month of Ramadan with his family.
Before he went home, he showed journalists how he could now write for the first time in more than 10 years:

If you thought his condition is still bad, you should see his condition BEFORE being hospitalised.
Video of him being interviewed by The Telegraph UK before he was admitted to hospital:





